Who it's for
You've been lifting for at least six months, you can train four days a week, and your main goal is to build muscle. If you're a beginner, start with the 3-day full body programme first; it'll get you further, faster.
The week
Upper, Lower, rest, Upper, Lower, rest, rest is the classic layout (Mon/Tue/Thu/Fri). Any arrangement works as long as you don't put the two lower days back to back.